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Heparin Sodium

Heparin Sodium

CAS No.:9041-08-1 MF:(C12H16NS2Na3)20 Appearance:White Powder Specifications 1. Product: Heparin sodium 2. Speicfication: EP 7.0, USP 34 3. Reasonable price 4. Good service Specification

Detailed description

CAS No.:9041-08-1

MF:(C12H16NS2Na3)20

Appearance:White Powder

Specifications

1. Product: Heparin sodium 

2. Speicfication: EP 7.0, USP 34 

3. Reasonable price 

4. Good service

Specification

Test

Acceptance criteria

Origin

Porcine intestinal mucosa

Appearance

White or almost white, hygroscopic powder

Solubility

Freely soluble in water

Identification

A:delays the clotting of sheep plasma
B:1H-NMR: complies with EP 7.0 specification of heparin sodium about 1H-NMR requirements
C:Chromatographic identity: the retention time and the shape of the principal peak from the sample solution are similar to that from the standard solution
D:complies with the test for sodium

Appearance of solution

Clear and not more intensely colored than intensity 5 of reference solution

pH

5.5~8.0

Nitrogen

1.5%~2.5%

Sodium

9.5%~12.5%

Nucleotide impurities

260nm: not greater than 0.15

Protein

Not more than 0.5%

Related substances

Dermatan sulfate: Not more than 2.0%
Total impurities: Not more than 3.0%

Galactosamine

Not more than 1.0%

Heavy metals

Not more than 20 ppm

Loss on drying

Not more than 8.0%

Bacterial endotoxins

Less than 0.01 IU/heparin IU

Potency

At least 180 IU/mg

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